The Human CD326 Monoclonal Antibody (FITC Conjugated 9C4) is a cutting-edge tool designed for researchers studying CD326, a key cell surface marker involved in various cellular processes. This high-quality antibody, carefully developed and validated by Assay Genie, offers exceptional specificity and sensitivity for detecting CD326 in human samples, making it an invaluable asset in a wide range of research applications.CD326, also known as EpCAM, is a transmembrane glycoprotein with important implications in cell adhesion and signaling. Its involvement in processes such as proliferation, differentiation, and migration renders it a fascinating target for investigations spanning fields like stem cell biology, cancer research, and developmental biology. By targeting CD326 with this monoclonal antibody, researchers can effectively study its expression, localization, and function in diverse cell types and experimental contexts.
With its FITC conjugation, the 9C4 monoclonal antibody allows for easy and efficient fluorescent detection of CD326, facilitating precise localization and quantification of the protein within cells or tissues. This feature expands the utility of the antibody in flow cytometry, immunofluorescence, and other imaging techniques, enabling researchers to gain deeper insights into the roles played by CD326 in normal physiology and disease states.In conclusion, the Human CD326 Monoclonal Antibody (FITC Conjugated 9C4) from Assay Genie represents a valuable resource for scientists interested in unraveling the complexities of CD326 biology. Its reliability, specificity, and versatility make it a potent tool for driving forward our understanding of cellular dynamics and disease mechanisms, paving the way for innovative discoveries and therapeutic advancements.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P16422
Gene ID:
4072
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD326 is also known as Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, and TROP1. CD326 is a type I transmembrane protein containing six disulfide bridges and one THYRO domain. This cell surface glycosylated 40 kD protein is highly expressed in bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin. Recently, it has been reported that CD326 expression occurs during the early steps of erythrogenesis. CD326 functions as a homotypic calcium-independent cell adhesion molecule and is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. CD326 antigen is an immunotherapeutic target for the treatment of human carcinomas.