The Human CD326 Monoclonal Antibody (APC-conjugated, 9C4-Agel1821) from Assay Genie is a cutting-edge tool for researchers studying CD326, a cell surface marker predominantly associated with epithelial cell populations. This highly specific monoclonal antibody is engineered for exceptional performance in flow cytometry applications, allowing for precise identification and analysis of CD326-expressing cells in various human samples.CD326, also known as EpCAM (Epithelial Cell Adhesion Molecule), plays a crucial role in cell adhesion and signaling processes, particularly in epithelial tissues and carcinomas. Its involvement in cancer progression and metastasis makes it a key target for studies in oncology and stem cell research.
By utilizing this APC-conjugated monoclonal antibody, researchers can gain valuable insights into the role of CD326 in tumor biology, epithelial cell differentiation, and regenerative medicine.With its high specificity and sensitivity, the Human CD326 Monoclonal Antibody (APC-conjugated, 9C4-Agel1821) offers a reliable solution for investigating CD326 expression patterns and dynamics in both normal and pathological conditions. Advance your research and unlock the potential of CD326 in understanding cellular behavior and disease mechanisms with this advanced antibody tool from Assay Genie.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P16422
Gene ID:
4072
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD326 is also known as Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, and TROP1. CD326 is a type I transmembrane protein containing six disulfide bridges and one THYRO domain. This cell surface glycosylated 40 kD protein is highly expressed in bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin. Recently, it has been reported that CD326 expression occurs during the early steps of erythrogenesis. CD326 functions as a homotypic calcium-independent cell adhesion molecule and is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. CD326 antigen is an immunotherapeutic target for the treatment of human carcinomas.