The Human CD32 Monoclonal Antibody PE/Cyanine7 Conjugated (IV.3) is a cutting-edge tool designed for precise immunological studies and flow cytometry analysis. This monoclonal antibody is specifically engineered to target the CD32 protein, a crucial molecule involved in immune responses and cell signaling pathways.At AssayGenie, we pride ourselves on delivering high-quality antibodies that enable researchers to delve deeper into the intricate mechanisms of the immune system. The CD32 Monoclonal Antibody PE/Cyanine7 Conjugated (IV.3) is meticulously validated for use in flow cytometry applications, providing accurate and reliable results on human samples.
By harnessing the power of this innovative antibody, researchers can gain valuable insights into the functionality of CD32 in various cell types, paving the way for advancements in immunology, cancer research, and beyond. Uncover the mysteries of immune regulation with the Human CD32 Monoclonal Antibody PE/Cyanine7 Conjugated (IV.3) from AssayGenie – your key to unlocking new discoveries in the realm of immunology.
Product Title:
PE/Cyanine7 Anti-Human CD32 Antibody [IV-3]
SKU:
AGEL1077
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
IV-3
Synonyms:
Low affinity immunoglobulin gamma Fc region receptor II-b;FCGR2B;IgG Fc receptor II-b;CDw32;Fc-gamma RII-b;Fc-gamma-RIIb;FcRII-b;CD32;FCG2; IGFR2;
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P31994
Gene ID:
2212
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).