The Human CD3 Monoclonal Antibody (PERCP-CY5.5) is a vital tool for immunology research, designed to specifically target and detect CD3 proteins found on human T cells. This monoclonal antibody, conjugated with PERCP-CY5.5, provides high specificity and sensitivity in flow cytometry applications, enabling accurate analysis of T cell populations.CD3 is a crucial component of the T cell receptor complex, essential for T cell activation and function in the immune response. This antibody, clone OKT3, offers researchers a reliable reagent to investigate T cell biology, immune responses, and T cell-mediated diseases.
Its validated performance in flow cytometry ensures precise identification and quantification of CD3-expressing cells in diverse experimental settings.By utilizing the Human CD3 Monoclonal Antibody (PERCP-CY5.5), researchers can delve deep into the mechanisms underlying T cell activation, differentiation, and function, paving the way for a better understanding of immune responses and the development of novel therapeutic strategies for immunological disorders and diseases.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P07766
Gene ID:
916
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.