The Human CD3 Monoclonal Antibody PE-Cyanine7 Conjugated (OKT3) AGEL0603 is a specialized reagent tailored for applications in immunology research. This monoclonal antibody specifically targets the CD3 antigen found on human T-cells, a crucial component of the immune system responsible for orchestrating immune responses. The antibody is conjugated with PE-Cyanine7, a fluorescent dye, allowing for easy visualization and analysis in flow cytometry and immunofluorescence experiments.The CD3 antigen is integral for T-cell activation and function, making it a key player in adaptive immune responses. By targeting CD3, researchers can investigate T-cell dynamics, activation states, and interactions in various experimental settings.
The OKT3 monoclonal antibody provides a reliable tool for studying T-cell biology, immune system function, and immunotherapy development.With its high specificity and validated performance in human samples, the OKT3 antibody opens opportunities for exploring T-cell-mediated immune responses in health and disease. Whether studying autoimmune disorders, infectious diseases, or immunotherapy strategies, this conjugated monoclonal antibody offers a valuable resource for advancing our understanding of T-cell biology and immunological processes.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P07766
Gene ID:
916
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.