PE/Cyanine5 Anti-Human CD27 Antibody [O323] (AGEL1710)

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SKU:
AGEL1710
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5 Anti-Human CD27 Antibody [O323]

The Human CD27 Monoclonal Antibody (PE/Cyanine5 Conjugated) (AGEL1710) is a powerful tool for research involving CD27, a cell surface molecule known for its role in immune cell signaling and activation. This antibody, specifically designed for use in flow cytometry applications, is raised in a monoclonal system to ensure high specificity and sensitivity in detecting CD27 expression in human samples.CD27, a member of the tumor necrosis factor receptor superfamily, is pivotal in regulating immune responses and promoting B-cell differentiation and survival. Its involvement in T-cell activation and memory formation also underscores its importance in immune system function. The ability of this antibody to specifically bind to CD27 allows for precise identification and quantification of CD27-expressing cells, facilitating detailed analysis of immune cell subsets and their responses in various experimental settings.

With its validated performance in flow cytometry, the Human CD27 Monoclonal Antibody (PE/Cyanine5 Conjugated) (AGEL1710) is an essential tool for researchers delving into immunology, oncology, and infectious diseases. By elucidating the functions of CD27 in immune regulation and host defense mechanisms, this antibody aids in advancing our understanding of immune responses and holds promise for developing novel therapeutic strategies targeting CD27-related pathways.

Product Title:PE/Cyanine5 Anti-Human CD27 Antibody [O323]
SKU:AGEL1710
Size:20 Tests, 100 Tests, 200 Tests
Clone No:O323
Synonyms:CD27L receptor;T-cell activation antigen CD27;T14;S152;TNFRSF7;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P26842
Gene ID:939
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.

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