The Human CD27 Monoclonal Antibody (AF488 Conjugated) is a cutting-edge tool for researchers in the field of immunology and cell biology. This antibody, with the catalog number O323-AGEL1714, is specifically designed to target the CD27 protein, a crucial cell surface molecule implicated in immune responses and T cell activation.Utilizing advanced conjugation technology, this monoclonal antibody is labeled with AF488, a high-performance fluorescent dye that allows for precise and sensitive detection of CD27 in various experiments. With a high degree of specificity and sensitivity, researchers can confidently study the expression and localization of CD27 in different cell types and tissues.Whether used in flow cytometry, immunofluorescence, or immunohistochemistry applications, the Human CD27 Monoclonal Antibody (AF488 Conjugated) offers reliable and reproducible results.
Its versatility and ease of use make it an essential tool for investigating immune responses, lymphocyte activation, and immune cell subpopulations in both basic research and clinical studies.By unlocking the intricacies of CD27 function and regulation, researchers can gain deeper insights into immune system dynamics, paving the way for the development of novel therapeutic strategies for immune-related disorders, infectious diseases, and cancer. Take your research to the next level with the Human CD27 Monoclonal Antibody (AF488 Conjugated) and uncover new possibilities in the realm of immunology.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P26842
Gene ID:
939
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.