The Human CD21 Monoclonal Antibody PE-Conjugated (BU32) is a powerful tool for researchers studying the CD21 antigen, a key cell surface marker involved in immune responses and B cell activation. This antibody, conjugated to phycoerythrin (PE), allows for efficient detection and analysis of CD21 in human samples, making it ideal for flow cytometry and immunofluorescence applications. CD21, also known as complement receptor 2 (CR2), plays a crucial role in the activation of B cells and the regulation of humoral immune responses. By targeting CD21, researchers can gain insights into the functioning of the immune system and its response to various antigens.
This antibody specifically binds to CD21, enabling precise identification and characterization of B cells expressing this antigen.In the field of immunology and infectious diseases research, the Human CD21 Monoclonal Antibody PE-Conjugated (BU32) serves as a valuable tool for investigating immune cell interactions, antigen presentation, and B cell signaling pathways. Its high specificity and sensitivity make it an essential reagent for studies focused on understanding the role of CD21 in immunity and developing potential therapeutic interventions targeting this crucial immune regulator.
Product Title:
PE Anti-Human CD21 Antibody [BU32]
SKU:
AGEL0204
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
BU32
Synonyms:
Complement receptor type 2;CR2;Cr2;Complement C3d receptor;Epstein-Barr virus receptor;EBV receptor;CD21;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
PE
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P20023
Gene ID:
1380
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD21 is a 145 kD transmembrane protein also known as complement C3d receptor (C3dR), complement receptor 2 (CR2), and Epstein-Barr virus receptor. CD21 is expressed on B cells, follicular dendritic cells, subsets of normal thymocytes and T cells, and some epithelial cells. CD21 is the receptor used by Epstein-Barr virus to infect B cells and is also the complement receptor for C3d. CD21 has also been shown to interact with a number of proteins, including CD23, CD19, annexin VI, CD81, iC3b, complement receptor 1 (CR1, CD35), and interferon-alpha 1 (IFN-α1).