Human CD200 Recombinant Protein (RPPB3108)
- SKU:
- RPPB3108
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- CD200
- Synonyms:
- MOX1
- MOX2
- MRC
- OX-2
- Source:
- Escherichia Coli
- Uniprot:
- P41217
Frequently bought together:
Description
| Product Name: | Human CD200 Recombinant Protein |
| Product Code: | RPPB3108 |
| Size: | 20µg |
| Species: | Human |
| Target: | CD200 |
| Synonyms: | MOX1, MOX2, MRC, OX-2, OX-2 membrane glycoprotein, CD_antigen, CD200. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | CD200 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSQVQVVTQ DEREQLYTPA SLKCSLQNAQ EALIVTWQKK KAVSPENMVT FSENHGVVIQ PAYKDKINIT QLGLQNSTIT FWNITLEDEG CYMCLFNTFG FGKISGTACL TVYVQPIVSL HYKFSEDHLN ITCSATARPA PMVFWKVPRS GIENSTVTLS HPNGTTSVTS ILHIKDPKNQ VGKEVICQVL HLGTVTDFKQ TVNKG |
CD200 is a type-1 membrane glycoprotein which is a part of the immunoglobulin superfamily due to its 2 immunoglobulin domains. CD200 regulates myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in various tissues. CD200 is also Costimulates T-cell proliferation.
CD200 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 225 amino acids (31-232 a.a) and having a molecular mass of 24.8kDa. CD200 is fused to a 23 amino acid His-tag at N-terminus.
| UniProt Protein Function: | Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues. |
| NCBI Summary: | This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016] |
| UniProt Code: | P41217 |
| NCBI GenInfo Identifier: | 311033489 |
| NCBI Gene ID: | 4345 |
| NCBI Accession: | P41217.4 |
| UniProt Secondary Accession: | P41217,Q6J2Q6, Q6PIQ4, Q8TB85, Q9H3J3, B3KQI1, B4DLW9 D3DN65, |
| UniProt Related Accession: | P41217 |
| Molecular Weight: | 32,975 Da |
| NCBI Full Name: | OX-2 membrane glycoprotein |
| NCBI Synonym Full Names: | CD200 molecule |
| NCBI Official Symbol: | CD200 |
| NCBI Official Synonym Symbols: | MRC; MOX1; MOX2; OX-2 |
| NCBI Protein Information: | OX-2 membrane glycoprotein |
| UniProt Protein Name: | OX-2 membrane glycoprotein |
| UniProt Synonym Protein Names: | CD_antigen: CD200 |
| UniProt Gene Name: | CD200 |
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