GenieFluor 647 Anti-Human CD20 Antibody [BCA/B20] (AGEL0921)

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SKU:
AGEL0921
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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GenieFluor 647 Anti-Human CD20 Antibody [BCA/B20]

The Human CD20 Monoclonal Antibody AF647 Conjugated (BCA-B20, AGEL0921) is a specialized tool for researchers interested in investigating the CD20 protein, a key marker found on the surface of B cells. This monoclonal antibody, conjugated with AF647 for enhanced detection capabilities, is tailored for use in flow cytometry and immunofluorescence applications. By specifically targeting the CD20 antigen, this antibody facilitates precise identification and analysis of B cells in various research settings.CD20, a transmembrane protein primarily expressed on B lymphocytes, plays a crucial role in B cell activation, proliferation, and differentiation, making it a pivotal target for immunology and oncology studies.

With its involvement in various B cell-related diseases, such as lymphomas and autoimmune disorders, understanding the function and expression of CD20 is instrumental in developing targeted therapies and diagnostic approaches. Researchers looking to delve into B cell biology, immunotherapy, or lymphoproliferative disorders will find this antibody invaluable in their investigations.

Product Title:GenieFluor 647 Anti-Human CD20 Antibody [BCA/B20]
SKU:AGEL0921
Size:20 Tests, 100 Tests, 200 Tests
Clone No:BCA/B20
Synonyms:B-lymphocyte antigen CD20;MS4A1;B-lymphocyte surface antigen B1;Bp35;Leukocyte surface antigen Leu-16;Membrane-spanning 4-domains subfamily A member 1;MS4A1;CD20;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:Genie Fluor 647 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11836
Gene ID:931
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

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