The Human CD2 Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated) TS1/8 (AGEL1771) available at Assaygenie is a powerful tool for research involving the CD2 cell surface molecule. CD2, a glycoprotein expressed on T cells, natural killer cells, and thymocytes, serves as a crucial T cell co-stimulatory receptor involved in immune cell activation and adhesion.This monoclonal antibody, conjugated with PERCP-Cyanine5.5, specifically binds to CD2, allowing for the detection and analysis of CD2-expressing cells in various biological samples. Its high reactivity with human samples ensures reliable results in flow cytometry and immunofluorescence applications. With its validated performance in cell staining and cell sorting experiments, this antibody is essential for studies in immunology, cell biology, and immunotherapy research.
Understanding the role of CD2 in immune cell signaling and immune response regulation is fundamental for elucidating the mechanisms of immune activation and tolerance. The Human CD2 Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated) TS1/8 (AGEL1771) from Assaygenie provides researchers with a valuable tool to explore the functions of CD2-expressing cells and their implications in various physiological and pathological processes, including immune disorders, infectious diseases, and cancer immunotherapy.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06729
Gene ID:
914
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD2 is a 50 kD type I transmembrane glycoprotein also known as LFA-2, T11, and sheep red blood cell receptor (SRBC-R). This immunoglobulin superfamily member is expressed on thymocytes, T lymphocytes, NK cells, and thymic B cell subsets. The major ligand for CD2 is CD58 (also known as LFA-3). CD2 has also been reported to bind CD48, CD59, and CD15. CD2 plays a critical role in alternative T cell activation, T cell signaling, and cell-cell adhesion.