The Human CD2 Monoclonal Antibody (PE/Cyanine7 Conjugated, TS1/8) is a cutting-edge tool designed to facilitate research into CD2, a cell surface glycoprotein crucial for immune cell signaling and activation. This monoclonal antibody, conjugated with PE/Cyanine7, exhibits high specificity and sensitivity towards CD2 on human samples. It is meticulously validated for flow cytometry applications, enabling precise detection and analysis of CD2 expression in various cell populations.CD2 is a key player in T cell activation and adhesion processes, making it a fundamental component in the immune response cascade.
Understanding the role of CD2 in immune cell interactions is essential for unraveling mechanisms underlying various diseases, including autoimmune disorders, infectious diseases, and immune-related dysfunctions. The Human CD2 Monoclonal Antibody (PE/Cyanine7 Conjugated, TS1/8) provides researchers with a powerful tool to delve into the intricate functions of CD2, paving the way for advancements in immunology research and therapeutic strategies targeting immune-related conditions.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06729
Gene ID:
914
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD2 is a 50 kD type I transmembrane glycoprotein also known as LFA-2, T11, and sheep red blood cell receptor (SRBC-R). This immunoglobulin superfamily member is expressed on thymocytes, T lymphocytes, NK cells, and thymic B cell subsets. The major ligand for CD2 is CD58 (also known as LFA-3). CD2 has also been reported to bind CD48, CD59, and CD15. CD2 plays a critical role in alternative T cell activation, T cell signaling, and cell-cell adhesion.