The Human CD2 Monoclonal Antibody (FITC Conjugated, TS1/8) is a valuable tool for research involving CD2, a cell surface glycoprotein predominantly found on T cells and natural killer cells. This antibody, conjugated with FITC for fluorescent detection, is specifically designed for use in flow cytometry and immunofluorescence applications. It binds to the CD2 protein, allowing for precise identification and analysis of CD2-expressing cells in various biological samples.CD2 plays a crucial role in cell adhesion and activation, particularly in T cell signaling and immune responses. Its presence on T cells makes it a key marker for T cell identification and characterization.
The CD2 Monoclonal Antibody is highly specific for human samples and provides reliable results in experimental settings focused on immunology, infectious diseases, and transplantation research.Given the central role of CD2 in immune cell interactions and immune system function, this antibody is a valuable tool for investigating T cell activation, differentiation, and responses to antigens. Understanding the dynamics of CD2 expression and function can offer insights into various immunological processes and aid in the development of targeted therapeutics for immune-related disorders and conditions.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06729
Gene ID:
914
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD2 is a 50 kD type I transmembrane glycoprotein also known as LFA-2, T11, and sheep red blood cell receptor (SRBC-R). This immunoglobulin superfamily member is expressed on thymocytes, T lymphocytes, NK cells, and thymic B cell subsets. The major ligand for CD2 is CD58 (also known as LFA-3). CD2 has also been reported to bind CD48, CD59, and CD15. CD2 plays a critical role in alternative T cell activation, T cell signaling, and cell-cell adhesion.