The FITC-Conjugated Human CD1a Monoclonal Antibody (OKT-6) from Assay Genie (AGEL1587) is a vital tool for researchers studying CD1a, a cell surface protein involved in antigen presentation and immune response modulation. This monoclonal antibody, specifically targeting human samples, is conjugated with FITC for easy visualization and detection in flow cytometry and immunofluorescence applications.CD1a is a member of the CD1 family of proteins, which are crucial for presenting lipid antigens to T cells and initiating immune responses. The OKT-6 antibody, known for its high specificity and sensitivity, provides researchers with a reliable tool for studying CD1a expression and function in various cell types and tissues.
By targeting CD1a, researchers can gain insights into the role of lipid antigen presentation in immune surveillance, autoimmunity, and infectious diseases. This antibody is a valuable resource for investigations into the mechanisms underlying immune activation and regulation, offering new perspectives on immunological processes and potential therapeutic targets.With the FITC-Conjugated Human CD1a Monoclonal Antibody (OKT-6) from Assay Genie, researchers can advance their understanding of CD1a biology and its impact on immune responses, paving the way for innovative discoveries in immunology and related fields.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06126
Gene ID:
909
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD1a is a 49 kD member of the immunoglobulin superfamily also known as T6 and R4. It is a type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. CD1a plays a role in non-peptide glycolipid antigen presentation to CD1-restricted T cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation, CD1a has been implicated in thymic T cell development.