The Human CD18 Monoclonal Antibody (TS1/18) is a specialized research tool offered by AssayGenie for investigations involving the CD18 molecule, a key component of integrin complexes essential for cell adhesion and migration in immune cells. This monoclonal antibody, designated TS1/18, has been meticulously engineered and validated for specific binding to human CD18, ensuring high sensitivity and reliability in experimental settings.CD18, also known as integrin beta-2 subunit, plays a pivotal role in leukocyte trafficking and immune response regulation. By targeting CD18, researchers can study the mechanisms underlying cell-cell interactions, inflammatory processes, and immune cell activation.
The TS1/18 monoclonal antibody opens up avenues for in-depth exploration of CD18 function in various cellular contexts, offering valuable insights into conditions such as inflammation, autoimmune diseases, and infectious disorders.With its proven efficacy in various laboratory techniques, including immunoprecipitation and flow cytometry, the Human CD18 Monoclonal Antibody (TS1/18) from AssayGenie is a versatile tool for advancing research in immunology, inflammation, and infectious disease. Unlock the potential of CD18 biology with this reliable antibody and uncover new knowledge about immune system function and dysfunction.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD18 is a 90-95 kD type I transmembrane protein also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in adhesion and signaling in hematopoietic cells.