The Human CD18 Monoclonal Antibody (PE/Cyanine7 Conjugated, TS1/18) is a powerful tool for research involving CD18, a key adhesion molecule crucial for leukocyte recruitment and immune system function. This monoclonal antibody, conjugated to PE/Cyanine7 for fluorescence detection, is specifically designed for flow cytometry applications.CD18, also known as integrin beta-2, forms the β2 subunit of leukocyte integrins and plays a pivotal role in cell adhesion and migration. By targeting CD18, this antibody enables precise detection and analysis of leukocytes in various biological samples, making it ideal for immune cell profiling and immune response studies.
Through its unique specificity and high reactivity with human CD18, this monoclonal antibody provides researchers with a reliable tool to investigate leukocyte activation and migration processes. Its application in flow cytometry allows for detailed phenotypic and functional analysis of immune cells, making it an indispensable resource for immunology research, inflammation studies, and investigations into various immune-mediated diseases.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05107
Gene ID:
3689
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD18 is a 90-95 kD type I transmembrane protein also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in adhesion and signaling in hematopoietic cells.