PE/Cyanine5 Anti-Human CD18 Antibody [TS1/18.1.2.11] (AGEL0981)

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SKU:
AGEL0981
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5 Anti-Human CD18 Antibody [TS1/18.1.2.11]

The Human CD18 Monoclonal Antibody PE-Cyanine5 Conjugated (TS1/18) (AGEL0981) is an essential tool for researchers studying the CD18 protein, a key component of integrin receptors involved in mediating cell adhesion and migration. This antibody, derived from a monoclonal source, is specifically designed for use in flow cytometry applications, allowing for precise detection and quantification of CD18 expression on human cell samples.CD18, also known as integrin beta-2, plays a crucial role in various cellular processes, including leukocyte recruitment, immune response regulation, and inflammatory signaling. Its interaction with other integrin subunits forms functionally important adhesion molecules implicated in numerous physiological and pathological conditions.

The targeted binding of the TS1/18 antibody to the CD18 protein provides researchers with a reliable tool to investigate the dynamics of integrin-mediated adhesion and signaling pathways in different cell types and experimental settings.With its high specificity and validated performance in flow cytometry, the Human CD18 Monoclonal Antibody PE-Cyanine5 Conjugated (TS1/18) (AGEL0981) is a valuable asset for studies focused on understanding the role of integrins in immune responses, cell adhesion, and disease processes. Its utility extends to research areas such as immunology, inflammation, and cancer biology, offering researchers a versatile reagent for advancing their investigations into integrin biology and associated pathologies.

Product Title:PE/Cyanine5 Anti-Human CD18 Antibody [TS1/18.1.2.11]
SKU:AGEL0981
Size:20 Tests, 100 Tests, 200 Tests
Clone No:TS1/18.1.2.11
Synonyms:Integrin beta-2;Itgb2;Cell surface adhesion glycoproteins LFA-1/CR3/p150+95 subunit beta;Complement receptor C3 subunit beta;CD18;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05107
Gene ID:3689
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD18 is a 90-95 kD type I transmembrane protein also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in adhesion and signaling in hematopoietic cells.

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