The Human CD18 Monoclonal Antibody PE Conjugated (TS1/18) (AGEL0242) is a cutting-edge tool for researchers studying cell adhesion and inflammation mechanisms. This antibody, specifically targeting the CD18 protein, is conjugated with PE for flow cytometry applications, allowing for precise and efficient detection of CD18 expression in human samples.CD18, a subunit of the β2 integrin family, plays a crucial role in cell adhesion and migration processes essential for immune responses. By targeting CD18 with this monoclonal antibody, researchers can gain valuable insights into the mechanisms governing immune cell interactions and inflammatory pathways. This antibody is validated for use in flow cytometry, enabling accurate quantification of CD18 expression levels on various cell types, making it an invaluable tool for immunology and inflammation research.
Understanding the function and regulation of CD18 is fundamental for deciphering complex immunological processes and developing targeted therapies for inflammatory disorders, autoimmune diseases, and other conditions related to aberrant immune responses. The Human CD18 Monoclonal Antibody PE Conjugated (TS1/18) (AGEL0242) offers researchers a powerful tool to advance their studies and contribute to the growing body of knowledge in immunology and inflammation research.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05107
Gene ID:
3689
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD18 is a 90-95 kD type I transmembrane protein also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in adhesion and signaling in hematopoietic cells.