The Human CD18 Monoclonal Antibody (APC Conjugated) TS1/18 recognizes CD18, a cell surface glycoprotein that forms a heterodimer with integrin beta 2 subunit to create the leukocyte-specific integrin, lymphocyte function-associated antigen-1 (LFA-1). LFA-1 is involved in various immune responses, including leukocyte migration and adhesion.This monoclonal antibody, labeled with APC for flow cytometry applications, is specifically designed for research involving CD18 in human samples. It allows for the detection and analysis of CD18 expression in a variety of cell types, facilitating studies in immunology, inflammation, and autoimmune diseases.
By targeting CD18, researchers can deepen their understanding of immune responses and inflammatory processes, potentially leading to the development of new therapeutic approaches for conditions where dysregulation of leukocyte function is a factor. The Human CD18 Monoclonal Antibody (APC Conjugated) TS1/18 is a valuable tool for investigating the role of CD18 in immune function and related pathologies.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05107
Gene ID:
3689
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD18 is a 90-95 kD type I transmembrane protein also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in adhesion and signaling in hematopoietic cells.
![APC Anti-Human CD18 Antibody [TS1/18.1.2.11] (AGEL0243)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/608x608/products/120586/118766/AGEL0243__55149__66228.1732013230.jpg?c=1 "APC Anti-Human CD18 Antibody [TS1/18.1.2.11] (AGEL0243)")
![APC Anti-Human CD18 Antibody [TS1/18.1.2.11] (AGEL0243)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/1280x1280/products/120586/118766/AGEL0243__55149__66228.1732013230.jpg?c=1&imbypass=on "APC Anti-Human CD18 Antibody [TS1/18.1.2.11] (AGEL0243)")
![Biotin Anti-Human CD18 Antibody [TS1/18.1.2.11] (AGEL0240)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/120583/118763/biotin-anti-human-cd18-antibody-ts118.1.2.11-agel0240__93787__26789.1732013228.jpg?c=1 "Biotin Anti-Human CD18 Antibody [TS1/18.1.2.11] (AGEL0240)")
![FITC Anti-Human CD18 Antibody [TS1/18.1.2.11] (AGEL0241)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/120584/118764/fitc-anti-human-cd18-antibody-ts118.1.2.11-agel0241__19722__73464.1732013229.jpg?c=1 "FITC Anti-Human CD18 Antibody [TS1/18.1.2.11] (AGEL0241)")
![PE Anti-Human CD18 Antibody [TS1/18.1.2.11] (AGEL0242)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/120585/118765/pe-anti-human-cd18-antibody-ts118.1.2.11-agel0242__76867__53726.1732013229.jpg?c=1 "PE Anti-Human CD18 Antibody [TS1/18.1.2.11] (AGEL0242)")
![Purified Anti-Human CD18 Antibody [TS1/18.1.2.11] (AGEL0239)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/120582/118762/AGEL0239__91215__18326.1732013228.jpg?c=1 "Purified Anti-Human CD18 Antibody [TS1/18.1.2.11] (AGEL0239)")
![GenieFluor 647 Anti-Human CD18 Antibody [TS1/18.1.2.11] (AGEL0985)](https://cdn11.bigcommerce.com/s-39x6lpnvxv/images/stencil/590x590/products/121598/119778/geniefluor-647-anti-human-cd18-antibody-ts118.1.2.11-agel0985__63252__75630.1732015177.jpg?c=1 "GenieFluor 647 Anti-Human CD18 Antibody [TS1/18.1.2.11] (AGEL0985)")