The Human CD18 Monoclonal Antibody (Alexa Fluor 488 Conjugated) TS1/18 is a cutting-edge tool for researchers studying immune system function and cell adhesion processes. This antibody, designated AGEL0244 by Assay Genie, is specifically designed to target CD18, a crucial protein involved in leukocyte adhesion and migration.CD18 plays a vital role in the immune response by mediating interactions between leukocytes and endothelial cells, orchestrating the movement of immune cells to sites of infection or inflammation. By specifically binding to CD18, this monoclonal antibody enables precise detection and visualization of the protein in various cell types and tissues.The fluorescent conjugation of the antibody with Alexa Fluor 488 enhances its utility in fluorescence-based applications, such as immunofluorescence microscopy and flow cytometry.
This allows for high-resolution imaging and accurate quantification of CD18 expression and localization within biological samples.Researchers in the fields of immunology, inflammation, and infectious diseases can leverage the Human CD18 Monoclonal Antibody (Alexa Fluor 488 Conjugated) TS1/18 to deepen their understanding of leukocyte function, immune cell trafficking, and inflammatory processes. Its reliability, specificity, and versatility make it a valuable tool for deciphering the intricate mechanisms governing immune responses and inflammatory diseases.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05107
Gene ID:
3689
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD18 is a 90-95 kD type I transmembrane protein also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in adhesion and signaling in hematopoietic cells.