The Human CD18 Monoclonal Antibody (AF647 Conjugated, TS1/18.1.2.11) is a cutting-edge tool for researchers investigating cell adhesion and immune response mechanisms. This antibody, offered by Assay Genie, is specifically designed for detecting the CD18 protein on human cells, a crucial component of integrin molecules involved in leukocyte adhesion and migration.With its AF647 conjugation, this monoclonal antibody provides high sensitivity and fluorescence signal, making it ideal for flow cytometry and immunofluorescence applications. Its specificity for human CD18 ensures accurate and reliable results in studies related to inflammatory processes, immune cell interactions, and immune-mediated diseases.
The TS1/18.1.2.11 antibody is rigorously validated by Assay Genie to guarantee high performance and reproducibility in experiments. Researchers in immunology, cell biology, and infectious disease fields can trust this monoclonal antibody to deliver precise and insightful data on CD18 expression and function in human cells, paving the way for innovative discoveries and therapeutic advancements in immune-related research.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05107
Gene ID:
3689
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD18 is a 90-95 kD type I transmembrane protein also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in adhesion and signaling in hematopoietic cells.
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