Human CD16b/FCGR3B Recombinant Protein (RPES0557)
- SKU:
- RPES0557
- Product type:
- Recombinant Protein
- Host species:
- E.coli
- Reactivity:
- Human
Frequently bought together:
Description
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Human CD16b/FCGR3B Recombinant Protein
Low affinity immunoglobulin gamma Fc region receptor III-B; also known as Fc-gamma RIII-beta; FcR-10; IgG Fc receptor III-1; FCG3; FCGR3; CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
| Product Name: | Human CD16b/FCGR3B Recombinant Protein (RPES0557) |
| Product Code: | RPES0557 |
| Size: | 50µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Low affinity immunoglobulin gamma Fc region receptor III-B, Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR6B,FCRIII,FCRIIIb |
| Accession: | O75015-1 |
| Sequence: | Met 18-Gly 193 |
| Fusion tag: | |
| Activity: | Measured by its ability to bind human IgG1 in a functional ELISA.2. Labeling ratio of biotin to protein: 5.51. |
| Endotoxin: | Please contact us for more information. |
| Protein Construction: | A DNA sequence encoding the mature form of human CD16b (O75015-1) (Met 18-Gly 193) was expressed and purified. The expressed protein was biotinylated in vitro. |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 20 kDa |
| Formulation: | Lyophilized from sterile PBS; pH 7.4 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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