Human CD155/PVR/NECL5 Recombinant Protein (RPES0441)

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SKU:
RPES0441
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
Frequently bought together:

Description

system_update_alt데이터시트

Human CD155/PVR/NECL5 Recombinant Protein

Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV); an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains; a transmembrane segment; and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms (?; β; ?; and ?) with identical extracellular domains.

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