The Human CD147 Monoclonal Antibody PE-Cyanine7 Conjugated (HIM6) is a cutting-edge tool for researchers studying CD147, a transmembrane glycoprotein involved in diverse physiological and pathological processes. This antibody, conjugated with PE-Cyanine7, provides excellent sensitivity and specificity for detecting CD147 in human samples. CD147, also known as EMMPRIN or basigin, is a multifunctional molecule that plays key roles in cell adhesion, signal transduction, and tumor progression. By targeting CD147, researchers can gain insights into its roles in cancer, inflammation, and tissue remodeling.
The HIM6 antibody offers researchers a reliable tool for flow cytometry and fluorescence-based assays, enabling precise analysis of CD147 expression in different cell types and tissues. Its versatility and high performance make it essential for studies in oncology, immunology, and cell biology. Utilizing this antibody can lead to a deeper understanding of CD147 biology and its potential as a therapeutic target in various disease contexts.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P35613
Gene ID:
682
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD147, also known as neurothelin or basigin, is a member of the Ig superfamily. It is a 55-65 kD type I transmembrane glycoprotein which is primarily expressed on leukocytes, erythrocytes, platelets, and endothelial cells. CD147 is reported to have a function during embryonal brain development and/or play a role in integrin-mediated adhesion in brain endothelia.