The Human CD147 Monoclonal Antibody (PE-Cyanine5 Conjugated) HIM6 (AGL0974) offered by AssayGenie is a cutting-edge tool for researchers studying CD147, a multifunctional transmembrane glycoprotein involved in numerous physiological and pathological processes. This antibody, derived from a monoclonal source, exhibits high specificity and sensitivity for human samples, making it a reliable choice for a range of experimental applications.CD147, also known as Basigin or EMMPRIN, is a key player in cell adhesion, migration, and signaling pathways, making it a compelling target for investigations in various fields, including cancer biology, immunology, and neuroscience. By effectively binding to the CD147 protein, the HIM6 antibody facilitates the visualization and analysis of CD147 expression in diverse cell types, providing valuable insights into its roles in disease progression and cellular function.
Researchers can leverage the PE-Cyanine5 conjugation of this antibody for flow cytometry analyses, enabling the precise quantification and characterization of CD147-expressing cells within complex biological samples. This functionality enhances the antibody's utility in elucidating the mechanisms through which CD147 influences cellular behavior and disease processes.With its robust performance and versatility, the Human CD147 Monoclonal Antibody (PE-Cyanine5 Conjugated) HIM6 (AGL0974) empowers researchers to delve deeper into the intricate functions of CD147, paving the way for innovative discoveries and impactful advancements in biomedical research.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P35613
Gene ID:
682
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD147, also known as neurothelin or basigin, is a member of the Ig superfamily. It is a 55-65 kD type I transmembrane glycoprotein which is primarily expressed on leukocytes, erythrocytes, platelets, and endothelial cells. CD147 is reported to have a function during embryonal brain development and/or play a role in integrin-mediated adhesion in brain endothelia.