The Human CD147 Monoclonal Antibody (FITC Conjugated) HIM6 (AGEL0970) offered by AssayGenie is a cutting-edge tool designed for researchers delving into the intricate world of CD147, a pivotal cell surface glycoprotein involved in numerous biological processes. The antibody, derived through meticulous monoclonal techniques, exhibits exceptional specificity towards human samples and is specially optimized for fluorescence-based assays.CD147, also known as Basigin or EMMPRIN, serves as a multifunctional molecule influencing diverse cellular functions, including cell adhesion, migration, and signaling. Its role in various physiological and pathological processes has propelled it into the spotlight of biomedical research, particularly in the realms of cancer biology, immunology, and inflammation.
With its FITC conjugation, the HIM6 antibody not only enables precise detection and visualization of CD147 within different cell types but also opens up avenues for exploring its dynamic localization and interactions within cellular microenvironments. This feature-rich antibody is poised to facilitate in-depth investigations into CD147's involvement in disease pathways and potential therapeutic targets.For scientists unraveling the complexities of CD147 biology and its implications in health and disease, the Human CD147 Monoclonal Antibody (FITC Conjugated) HIM6 (AGEL0970) is a potent ally, providing reliable and reproducible results crucial for advancing our understanding of this intriguing molecule's functions.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P35613
Gene ID:
682
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD147, also known as neurothelin or basigin, is a member of the Ig superfamily. It is a 55-65 kD type I transmembrane glycoprotein which is primarily expressed on leukocytes, erythrocytes, platelets, and endothelial cells. CD147 is reported to have a function during embryonal brain development and/or play a role in integrin-mediated adhesion in brain endothelia.