The Human CD134 Monoclonal Antibody (APC Conjugated) is a cutting-edge tool for researchers in the field of immunology, designed to facilitate the detection and analysis of CD134, a crucial cell surface molecule with implications in immune responses and regulatory functions. This high-quality antibody, labeled with APC for enhanced visibility and detection, is specifically targeted towards human samples, ensuring accurate results and reliable data interpretation.CD134, also known as OX40, is a co-stimulatory molecule that plays a pivotal role in regulating T cell activation, survival, and cytokine production. By targeting CD134, researchers can delve deeper into the intricate mechanisms of immune system modulation, paving the way for advancements in understanding autoimmune diseases, cancer immunotherapy, and infectious diseases.
The utilization of this monoclonal antibody opens up avenues for exploring the diverse functions of CD134 in various cell types, offering valuable insights into immunological processes and potential therapeutic targets.Whether investigating immune responses in cancer research or studying immunomodulatory pathways, the Human CD134 Monoclonal Antibody (APC Conjugated) serves as an indispensable tool for researchers seeking to unravel the complexities of immune regulation and its implications on human health and disease. Trust in this innovative antibody to elevate your research endeavors and unlock new discoveries in the dynamic realm of immunology.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P43489
Gene ID:
7293
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD134, also known as OX40 and TNFRSF4, is a 50 kD type I transmembrane glycoprotein. It is a member of the TNF receptor family. OX40 is expressed on activated T lymphocytes including Th1, Th2, Th17, and Treg cells. The interaction of OX40 with OX40L results in B cell proliferation and antibody secretion, regulation of primary T cell expansion, and T cell survival. OX40 influences the size of the T cell memory pool and regulation of CD4+ T cell tolerance.