PE Anti-Human CD127/IL-7RA Antibody [A019D5] (AGEL1783)

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SKU:
AGEL1783
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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PE Anti-Human CD127/IL-7RA Antibody [A019D5]

The Human CD127 (IL-7RA) Monoclonal Antibody, PE Conjugated (AGEL1783) from Assay Genie is a powerful tool for researchers studying the CD127 (IL-7RA) protein, a critical receptor involved in immune system function. This monoclonal antibody is conjugated with phycoerythrin (PE) for convenient detection and analysis in flow cytometry applications.The CD127 (IL-7RA) protein is essential for the development and function of immune cells, particularly T cells, and plays a crucial role in regulating immune responses. By targeting CD127, researchers can gain insights into various immunological processes, including immune cell development, activation, and differentiation.

With its high specificity and sensitivity to human CD127 (IL-7RA), this monoclonal antibody is ideal for use in flow cytometry assays to profile immune cell populations and investigate the role of CD127 in various immune-related diseases such as autoimmune disorders, infectious diseases, and cancer. Researchers can rely on the AGEL1783 antibody to provide accurate and reliable results for their experiments, advancing our understanding of immune system function and disease mechanisms.

Product Title:PE Anti-Human CD127/IL-7RA Antibody [A019D5]
SKU:AGEL1783
Size:20 Tests, 100 Tests, 200 Tests
Clone No:A019D5
Synonyms:Interleukin-7 receptor subunit alpha;IL-7RA;CDw127;CD127;IL-7Rα;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P16871
Gene ID:3575
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.

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