APC Anti-Human CD11c Antibody [BU15] (AGEL0448)

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SKU:
AGEL0448
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
BU15
Conjugation:
APC
Applications:
FC
Frequently bought together:

Description

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APC Anti-Human CD11c Antibody [BU15]

The Human CD11c Monoclonal Antibody (APC conjugated, BU15) is a valuable tool for research involving CD11c, a cell surface molecule that plays a key role in the immune system as a marker for dendritic cells. This monoclonal antibody, conjugated with APC for easy detection in flow cytometry experiments, is highly specific and reactive with human samples, making it ideal for immunology studies.With its ability to target the CD11c protein, this antibody allows for accurate detection and analysis of dendritic cells in various cell types. Its use is validated for flow cytometry applications, providing researchers with a reliable tool for studying immune responses and cell interactions in both health and disease.

CD11c is known for its involvement in antigen presentation and T-cell activation, making it a crucial molecule for understanding immune responses and developing targeted therapies for conditions such as cancer, autoimmune diseases, and inflammatory disorders. By using the Human CD11c Monoclonal Antibody (APC conjugated, BU15), researchers can gain valuable insights into the role of dendritic cells in the immune system and potentially discover new avenues for therapeutic interventions.

Product Title:APC Anti-Human CD11c Antibody [BU15]
SKU:AGEL0448
Size:20 Tests, 100 Tests, 200 Tests
Clone No:BU15
Synonyms:Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P20702
Gene ID:3687
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αX and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.

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