GenieFluor 647 Anti-Human CD11c Antibody [BU15] (AGEL1464)

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SKU:
AGEL1464
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a,k
Clone:
BU15
Conjugation:
AF 647
Frequently bought together:

Description

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GenieFluor 647 Anti-Human CD11c Antibody [BU15]

The Human CD11c Monoclonal Antibody (AF647 Conjugated, BU15, Agel1464) is a powerful tool for researchers studying immune cells expressing the CD11c antigen. This monoclonal antibody, conjugated with AF647 for fluorescent detection, specifically targets human CD11c, a key cell surface marker associated with dendritic cells and other immune cell populations.Ideal for flow cytometry and immunofluorescence applications, this antibody enables precise identification and quantification of CD11c-expressing cells in various biological samples. Its high specificity and sensitivity make it a valuable resource for investigating immune responses, antigen presentation, and dendritic cell function in both normal and pathological conditions.

The CD11c antigen is a crucial component of the immune system, involved in antigen capture, processing, and presentation, as well as immune cell activation and regulation. By targeting CD11c, researchers can gain insights into the role of dendritic cells in immunity, inflammation, and immune-related diseases, paving the way for advancements in immunotherapy, vaccine development, and immunological research.For scientists interested in unraveling the complexities of the immune system and exploring the diverse functions of CD11c-expressing cells, the Human CD11c Monoclonal Antibody (AF647 Conjugated, BU15, Agel1464) offers a reliable and specific tool to advance their research endeavors.

Product Title:GenieFluor 647 Anti-Human CD11c Antibody [BU15]
SKU:AGEL1464
Size:20 Tests, 100 Tests, 200 Tests
Clone No:BU15
Synonyms:Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 647 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P20702
Gene ID:3687
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αX and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.

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