PerCP Anti-Human CD11b Antibody [ICRF44] (AGEL1752)

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SKU:
AGEL1752
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a,k
Clone:
ICRF44
Conjugation:
PerCP
Frequently bought together:

Description

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PerCP Anti-Human CD11b Antibody [ICRF44]

The Human CD11b Monoclonal Antibody (PERCP conjugated, ICRF44) from Assay Genie (AGEL1752) is a powerful tool for researchers studying the CD11b protein, a key marker of immune cells involved in inflammation and immune responses. This monoclonal antibody, conjugated with PERCP for enhanced detection, specifically targets human CD11b and is ideal for flow cytometry and immunofluorescence applications.CD11b, also known as integrin alpha M, is an essential component of the innate immune system, playing a crucial role in cell adhesion and migration. Its expression on immune cells such as monocytes, macrophages, and neutrophils makes it a valuable target for understanding immune cell function in various physiological and pathological conditions.

Researchers can use this monoclonal antibody to accurately identify and quantify CD11b-expressing cells in complex biological samples, facilitating detailed analysis of immune cell populations.By utilizing the Human CD11b Monoclonal Antibody (PERCP conjugated, ICRF44) from Assay Genie, scientists can delve deeper into the role of CD11b in immune responses, inflammation, and disease pathogenesis. This cutting-edge antibody provides a reliable and specific tool for unraveling the complexities of immune cell biology, paving the way for new insights and potential therapeutic strategies in immunology and related research fields.

Product Title:PerCP Anti-Human CD11b Antibody [ICRF44]
SKU:AGEL1752
Size:20 Tests, 100 Tests, 200 Tests
Clone No:ICRF44
Synonyms:Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PerCP Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PerCP
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11215
Gene ID:3684
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2(CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.

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