FITC Anti-Human CD11a Antibody [TS1/22.1.1.13] (AGEL0962)

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SKU:
AGEL0962
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a,k
Clone:
TS1/22.1.1.13
Conjugation:
FITC
Frequently bought together:

Description

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FITC Anti-Human CD11a Antibody [TS1/22.1.1.13]

The Human CD11a Monoclonal Antibody (FITC Conjugated) TS1/22 (AGEL0962) is a valuable tool for researchers studying CD11a, a cell surface protein involved in immune cell adhesion and signaling. This monoclonal antibody, conjugated with FITC for convenient detection, is highly specific to human samples and has been validated for use in flow cytometry applications.CD11a, a subunit of the integrin receptor LFA-1, plays a vital role in mediating immune cell interactions and migration, making it a key target for investigations in immunology and inflammation. By specifically binding to CD11a, this antibody enables precise detection and analysis in various cell types, facilitating a deeper understanding of immune responses and related pathways.

With its ability to target CD11a, researchers can explore the functions and regulation of this important cell surface molecule in diverse contexts, including immune system disorders, inflammatory diseases, and potential therapeutic interventions. The Human CD11a Monoclonal Antibody (FITC Conjugated) TS1/22 (AGEL0962) provides a reliable tool for advancing research in immunology and related fields.

Product Title:FITC Anti-Human CD11a Antibody [TS1/22.1.1.13]
SKU:AGEL0962
Size:20 Tests, 100 Tests, 200 Tests
Clone No:TS1/22.1.1.13
Synonyms:Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P20701
Gene ID:3683
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

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