The Human CD11a Monoclonal Antibody (APC conjugated, R7/1) is a cutting-edge tool designed for researchers working in the field of immunology and cell biology. This antibody, offered by Assay Genie, targets the CD11a protein present on the surface of human cells and is specifically conjugated with APC for flow cytometry applications.CD11a, also known as integrin alpha L, plays a key role in cell adhesion and migration, particularly in immune responses and inflammation. The APC-conjugated CD11a antibody, clone R7/1, offers high sensitivity and specificity in detecting CD11a expression, making it an excellent tool for analyzing cell populations and studying cellular interactions in both normal and pathological conditions.
Validated for use in flow cytometry, the Human CD11a Monoclonal Antibody (APC conjugated, R7/1) provides researchers with a reliable reagent for investigating immune cell subsets, evaluating cell activation status, and unraveling complex cellular processes. Its application extends to studies on autoimmune diseases, inflammatory disorders, and immune cell dysregulation, offering valuable insights into disease mechanisms and potential therapeutic targets.Enhance your research with the precision and quality of the Human CD11a Monoclonal Antibody (APC conjugated, R7/1) from Assay Genie. Unveil the intricate world of immune cell biology and explore new dimensions in immunological research with this advanced antibody tool.
Product Title:
APC Anti-Human CD11a Antibody [R7-1]
SKU:
AGEL2087
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
R7-1
Synonyms:
Integrin alpha-L;LFA-1A;CD11A;ITGAL;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P20701
Gene ID:
3683
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).