GenieFluor 488 Anti-Human CD11a Antibody [R7-1] (AGEL2090)

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SKU:
AGEL2090
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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GenieFluor 488 Anti-Human CD11a Antibody [R7-1]

The Human CD11a Monoclonal Antibody (AF488 Conjugated) - R7-1 (AG2089) is a valuable tool for researchers studying the CD11a protein, a cell surface molecule associated with immune responses and cell adhesion. This monoclonal antibody, conjugated with AF488 for fluorescent detection, has been specifically designed for use in fluorescence-based assays and imaging techniques.CD11a, also known as integrin alpha L, is a crucial component of the Lymphocyte Function-associated Antigen 1 (LFA-1) complex, which plays a key role in immune cell interactions and migration. By targeting CD11a with this monoclonal antibody, researchers can analyze and visualize the expression and localization of CD11a in various cell types and tissues.

The CD11a Monoclonal Antibody (AF488 Conjugated) - R7-1 (AG2089) offers high specificity and sensitivity in detecting CD11a, making it an essential tool for studies focusing on immune cell activation, adhesion, and migration. Its fluorescent conjugation allows for easy visualization and quantification of CD11a expression, providing valuable insights into immune system function and potential therapeutic targets.

Product Title:GenieFluor 488 Anti-Human CD11a Antibody [R7-1]
SKU:AGEL2090
Size:20 Tests, 100 Tests, 200 Tests
Clone No:R7-1
Synonyms:Integrin alpha-L;LFA-1A;CD11A;ITGAL;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 488 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P20701
Gene ID:3683
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

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