APC Anti-Human CD117 Antibody [104D2] (AGEL1779)

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SKU:
AGEL1779
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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APC Anti-Human CD117 Antibody [104D2]

The Human CD117 Monoclonal Antibody (APC conjugated) (Clone 104D2) is a cutting-edge tool for researchers studying CD117, a cell surface receptor known for its role in hematopoiesis and stem cell differentiation. This antibody, specifically engineered for use in flow cytometry, offers precise detection and quantification of CD117-expressing cells in human samples.CD117, also known as c-Kit or stem cell factor receptor, is a crucial marker for identifying hematopoietic stem cells and various progenitor cell populations. Its involvement in cell proliferation, survival, and differentiation underscores its importance in both normal and pathological processes, such as cancer development and progression.

Targeting CD117 has shown promising results in cancer therapies, making it a hot topic for research in oncology and regenerative medicine.By utilizing the Human CD117 Monoclonal Antibody (APC conjugated), researchers can elucidate the complex roles of CD117 in different cell types and disease states, paving the way for innovative therapeutic approaches and advancing our understanding of hematopoiesis and cancer biology.

Product Title:APC Anti-Human CD117 Antibody [104D2]
SKU:AGEL1779
Size:20 Tests, 100 Tests, 200 Tests
Clone No:104D2
Synonyms:Mast/stem cell growth factor receptor Kit;Kit;SCFR;Proto-oncogene c-Kit;Tyrosine-protein kinase Kit;CD117;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P10721
Gene ID:3815
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cell factor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4% bone marrow cells), mast cells, and acute myeloid leukemia cells (AML). CD117 binding of c-Kit ligand induces phosphorylation of CD117 and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells.

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