The Human CD10 Monoclonal Antibody (FITC Conjugated) is a vital tool for research in the field of immunology. Specifically designed to target CD10, a cell surface molecule with significant implications in cell differentiation and immune responses, this antibody is optimized for use in various assays such as flow cytometry and immunofluorescence.CD10, also known as Common Acute Lymphoblastic Leukemia Antigen (CALLA), is a key marker in identifying and characterizing certain cell types, particularly in the context of hematological malignancies and lymphoid tissues. The FITC conjugation of this monoclonal antibody enables precise visualization and quantification of CD10 expression on cell surfaces, allowing researchers to identify and analyze specific cell populations with high accuracy.
By utilizing the Human CD10 Monoclonal Antibody (FITC Conjugated), researchers can delve deeper into the roles of CD10 in various physiological and pathological processes, including leukemia, lymphomas, and immune system functioning. This antibody serves as an invaluable tool for immunologists, oncologists, and researchers seeking to understand the intricate mechanisms underlying these conditions and develop targeted therapeutic strategies.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P08473
Gene ID:
4311
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD10 is a 100 kD neutral endopeptidase and a member of the metalloprotease family. It is a type II transmembrane protein also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin. CD10 is expressed on B cell precursors, T cell precursors, and neutrophils. CD10 is involved in B cell development and has been shown to bind opioid enkephalins, bradykinin, angiotensins I and II, and other biologically active peptides.