The CD10 Monoclonal Antibody (APC Conjugated) (HI10A-AGEL1718) is a crucial tool for researchers studying CD10, a cell surface marker with important implications in various biological processes. This monoclonal antibody, conjugated with APC for enhanced detection in flow cytometry applications, offers high specificity and sensitivity for human samples.CD10, also known as common acute lymphoblastic leukemia antigen (CALLA), is a key marker for identifying and characterizing different cell types, particularly in hematopoietic and lymphoid tissues. Its expression patterns can provide valuable insights into cell differentiation, maturation, and pathology.
The CD10 Monoclonal Antibody (APC Conjugated) facilitates the precise detection and analysis of CD10-positive cells, enabling researchers to explore its role in normal physiology and disease processes.Researchers in immunology, oncology, and related fields will find this antibody invaluable for investigating the functions and interactions of CD10 within the context of immune responses, leukemias, and lymphomas. By elucidating the molecular mechanisms involving CD10, this antibody contributes to advancing our understanding of various diseases and may pave the way for the development of targeted therapies and diagnostic tools.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P08473
Gene ID:
4311
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD10 is a 100 kD neutral endopeptidase and a member of the metalloprotease family. It is a type II transmembrane protein also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin. CD10 is expressed on B cell precursors, T cell precursors, and neutrophils. CD10 is involved in B cell development and has been shown to bind opioid enkephalins, bradykinin, angiotensins I and II, and other biologically active peptides.