Human CCL11/Eotaxin Recombinant Protein (RPES4715)
- SKU:
- RPES4715
- Product type:
- Recombinant Protein
- Host species:
- E.coli
- Reactivity:
- Human
Frequently bought together:
Description
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Human CCL11/Eotaxin Recombinant Protein
C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of allergic inflammatory reactions. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for CCL11 include CCR2, CCR3 and CCR5. However, it has been found that CCL11 has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3.
| Product Name: | Human CCL11/Eotaxin Recombinant Protein (RPES4715) |
| Product Code: | RPES4715 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Eotaxin, C-C Motif Chemokine 11, Eosinophil Chemotactic Protein, Small-Inducible Cytokine A11, CCL11, SCYA11 |
| Accession: | P51671 |
| Sequence: | Gly24-Pro97 |
| Fusion tag: | |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human C-C Motif Chemokine 11 is produced by our E.coli expression system and the target gene encoding Gly24-Pro97 is expressed. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 8.6 kDa |
| AP Mol Mass: | 14 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl?pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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