Human Cadherin1/CDH11 Recombinant Protein (RPES3758)
- SKU:
- RPES3758
- Product type:
- Recombinant Protein
- Host species:
- Human Cells
- Reactivity:
- Human
Frequently bought together:
Description
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Human Cadherin1/CDH11 Recombinant Protein
Cadherin-11; also known as OSF-4; Osteoblast cadherin and CDH11; is a type II classical cadherin from the cadherin superfamily; integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells; may thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in brain. Mature cadherin proteins consists of a large N-terminal extracellular domain; a single membrane-spanning domain; and a small; highly conserved C-terminal cytoplasmic domain. It is shown that cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme.
| Product Name: | Human Cadherin1/CDH11 Recombinant Protein (RPES3758) |
| Product Code: | RPES3758 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Cadherin 11 Type 2 OB-cadherin (Osteoblast), Cadherin 11 Type 2 OB-Cadherin (Osteoblast) Isoform CRA_c, CDH11 |
| Accession: | Q96CZ9 |
| Sequence: | Phe23-Thr617 |
| Fusion tag: | C-Fc-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Cadherin-11 is produced by our Mammalian expression system and the target gene encoding Phe23-Thr617 is expressed with a Fc; 6His tag at the C-terminus. |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 93.5 kDa |
| AP Mol Mass: | 110 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS; pH 7.4 . |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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