Human C19ORF80 Recombinant Protein (RPPB2933)

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SKU:
RPPB2933
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
C19ORF80
Synonyms:
Betatrophin
Synonyms:
Angiopoietin-like protein 8
Synonyms:
Lipasin
Synonyms:
C19orf80
Source:
Escherichia Coli
Uniprot:
Q6UXH0
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Description

Product Name:Human C19ORF80 Recombinant Protein
Product Code:RPPB2933
Size:10µg
Species:Human
Target:C19ORF80
Synonyms:Betatrophin, Angiopoietin-like protein 8, Lipasin, C19orf80, Angptl8, RIFL, TD26, PRO1185, PVPA599.
Source:Escherichia Coli
Physical Appearance:Filtered White lyophilized (freeze-dried) powder.
Formulation:C19ORF80 filtered (0.4 µm) and lyophilized from 0.5mg/ml in 0.05M Acetate buffer pH-4.0.
Solubility:It is recommended to add 0.1M Acetate buffer pH-4 to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10µg/ml. In higher concentrations the solubility of this antigen is limited. C19ORF80 is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Stability:Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
Purity:Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:MKHHHHHHASAPMGGPELAQ HEELTLLFHG TLQLGQALNG VYRTTEGRLT KARNSLGLYG RTIELLGQEV SRGRDAAQEL RASLLETQME EDILQLQAEA TAEVLGEVAQ AQKVLRDSVQ RLEVQLRSAW LGPAYREFEV LKAHADKQSH ILWALTGHVQ RQRREMVAQQ HRLRQIQERL HTAALPA

Chromosome 19 Open Reading Frame 80 (C19ORF80) is a significant new regulator of lipid metabolism which regulates serum triglyceride levels, possibly by promoting ANGPTL3 cleavage. C19ORF80 belongs to the ANGPTL protein family. C19ORF80 is a hormone which specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thus improving glucose tolerance. C19ORF80 is mainly expressed in the liver; it is also expressed in adipose tissues. C19ORF80 is expressed in response to food intake.

C19ORF80 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain (a.a 22-198) containing 187 amino acids including a 10 a.a N-terminal His tag. The total molecular mass is 21.1kDa (calculated).

UniProt Code:Q6UXH0
NCBI GenInfo Identifier:25013473
NCBI Gene ID:55908
NCBI Accession:
UniProt Related Accession:Q6UXH0
Molecular Weight:
NCBI Full Name:hepatocellular carcinoma associated protein TD26
NCBI Synonym Full Names:angiopoietin like 8
NCBI Official Symbol:ANGPTL8  
NCBI Official Synonym Symbols:RIFL; TD26; PRO1185; PVPA599; C19orf80  
NCBI Protein Information:angiopoietin-like protein 8
UniProt Protein Name:
UniProt Gene Name:
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