Human C19ORF80 Recombinant Protein (RPPB2933)
- SKU:
- RPPB2933
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Human
- Target:
- C19ORF80
- Synonyms:
- Betatrophin
- Angiopoietin-like protein 8
- Lipasin
- C19orf80
- Source:
- Escherichia Coli
- Uniprot:
- Q6UXH0
Frequently bought together:
Description
| Product Name: | Human C19ORF80 Recombinant Protein |
| Product Code: | RPPB2933 |
| Size: | 10µg |
| Species: | Human |
| Target: | C19ORF80 |
| Synonyms: | Betatrophin, Angiopoietin-like protein 8, Lipasin, C19orf80, Angptl8, RIFL, TD26, PRO1185, PVPA599. |
| Source: | Escherichia Coli |
| Physical Appearance: | Filtered White lyophilized (freeze-dried) powder. |
| Formulation: | C19ORF80 filtered (0.4 µm) and lyophilized from 0.5mg/ml in 0.05M Acetate buffer pH-4.0. |
| Solubility: | It is recommended to add 0.1M Acetate buffer pH-4 to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10µg/ml. In higher concentrations the solubility of this antigen is limited. C19ORF80 is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture. |
| Stability: | Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MKHHHHHHASAPMGGPELAQ HEELTLLFHG TLQLGQALNG VYRTTEGRLT KARNSLGLYG RTIELLGQEV SRGRDAAQEL RASLLETQME EDILQLQAEA TAEVLGEVAQ AQKVLRDSVQ RLEVQLRSAW LGPAYREFEV LKAHADKQSH ILWALTGHVQ RQRREMVAQQ HRLRQIQERL HTAALPA |
Chromosome 19 Open Reading Frame 80 (C19ORF80) is a significant new regulator of lipid metabolism which regulates serum triglyceride levels, possibly by promoting ANGPTL3 cleavage. C19ORF80 belongs to the ANGPTL protein family. C19ORF80 is a hormone which specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thus improving glucose tolerance. C19ORF80 is mainly expressed in the liver; it is also expressed in adipose tissues. C19ORF80 is expressed in response to food intake.
C19ORF80 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain (a.a 22-198) containing 187 amino acids including a 10 a.a N-terminal His tag. The total molecular mass is 21.1kDa (calculated).
| UniProt Code: | Q6UXH0 |
| NCBI GenInfo Identifier: | 25013473 |
| NCBI Gene ID: | 55908 |
| NCBI Accession: | |
| UniProt Related Accession: | Q6UXH0 |
| Molecular Weight: | |
| NCBI Full Name: | hepatocellular carcinoma associated protein TD26 |
| NCBI Synonym Full Names: | angiopoietin like 8 |
| NCBI Official Symbol: | ANGPTL8 |
| NCBI Official Synonym Symbols: | RIFL; TD26; PRO1185; PVPA599; C19orf80 |
| NCBI Protein Information: | angiopoietin-like protein 8 |
| UniProt Protein Name: | |
| UniProt Gene Name: |
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