Human Beta-Defensin 1/DEFB1 Recombinant Protein (RPES3487)

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SKU:
RPES3487
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
Frequently bought together:

Description

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Human Beta-Defensin 1/DEFB1 Recombinant Protein

β-Defensin 1 (DEFB1) is a member of the β-defensin family, which is highly expressed by epithelial cells. β-defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal peptide. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. β-defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. Defects in β-Defensin-1 contribute to asthma diagnosis, with apparent gender-specific effects in human. β-defensin 1 may also play a role in the pathogenesis of severe sepsis. In addition, β-defensin 1 is associated with induction profiles in gingival keratinocytes.

Product Name:Human Beta-Defensin 1/DEFB1 Recombinant Protein (RPES3487)
Product Code:RPES3487
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Beta-Defensin 1, BD-1, hBD-1, Defensin Beta 1, DEFB1, BD1, HBD1
Accession:P60022
Sequence:Gly22-Lys68
Fusion tag:
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human beta-Defensin 1 is produced by our E.coli expression system and the target gene encoding Gly22-Lys68 is expressed.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:5.1 kDa
AP Mol Mass:6 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB, 130mM NaCl, pH 7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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