Human Beta-Arrestin 1/ARRB1 Recombinant Protein (RPES3444)

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SKU:
RPES3444
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human Beta-Arrestin 1/ARRB1 Recombinant Protein

β-Arrestin-1 (ARRB1) is a cytoplasmic protein that belongs to the arrestin family. ARRB1 is expressed at high levels in peripheral blood leukocytes and the central nervous system. ARRB1 regulates agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. ARRB1 acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. ARRB1 is believed to play a major role in regulating receptor-mediated immune functions. ARRB1 is involved in Toll-like receptor and IL-1 receptor signaling through the interaction with TRAF6.

Product Name:Human Beta-Arrestin 1/ARRB1 Recombinant Protein (RPES3444)
Product Code:RPES3444
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Beta-Arrestin-1, Arrestin Beta-1, ARRB1, ARR1
Accession:P49407
Sequence:Met 1-Arg418
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human beta-Arrestin 1 is produced by our E.coli expression system and the target gene encoding Met1-Arg418 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:48.1 kDa
AP Mol Mass:50 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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