Human AZGP1 Recombinant Protein (RPPB2833)
- SKU:
- RPPB2833
- Product type:
- Recombinant Protein
- Size:
- 10ug
- Species:
- Human
- Target:
- AZGP1
- Synonyms:
- Alpha-2-Glycoprotein 1
- Zinc-Binding
- Zinc-Alpha-2-Glycoprotein
- Zn-Alpha-2-Glycoprotein
- Source:
- Sf9 Insect cells
- Uniprot:
- P25311
Description
| Product Name: | Human AZGP1 Recombinant Protein |
| Product Code: | RPPB2833 |
| Size: | 10µg |
| Species: | Human |
| Target: | AZGP1 |
| Synonyms: | Alpha-2-Glycoprotein 1, Zinc-Binding, Zinc-Alpha-2-Glycoprotein, Zn-Alpha-2-Glycoprotein, Zn-Alpha-2-GP, ZAG, Testicular Tissue Protein Li 227, Alpha-2-Glycoprotein 1, Zinc, Alpha-2-Glycoprotein, Zinc, Zn-Alpha2-Glycoprotein, ZNGP1, ZA2G. |
| Source: | Sf9 Insect cells |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The AZGP1 solution (0.5mg/ml) contains 10% glycerol and Phosphate-Buffered Saline (pH 7.4). |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | QENQDGRYSL TYIYTGLSKH VEDVPAFQAL GSLNDLQFFR YNSKDRKSQP MGLWRQVEGM EDWKQDSQLQ KAREDIFMET LKDIVEYYND SNGSHVLQGR FGCEIENNRS SGAFWKYYYD GKDYIEFNKE IPAWVPFDPA AQITKQKWEA EPVYVQRAKA YLEEECPATL RKYLKYSKNI LDRQDPPSVV VTSHQAPGEK KKLKCLAYDF YPGKIDVHWT RAGEVQEPEL RGDVLHNGNG TYQSWVVVAV PPQDTAPYSC HVQHSSLAQP LVVPWEASLE HHHHHH |
Alpha-2-Glycoprotein 1 Zinc-Binding or AZGP1 is a protein, part of the MHC class 1 protein family. AZGP1 is thought to connect to prolactin-inducible protein (PIP), and not to , B 2-microglobulin (MHC light chain). AZGP1 is secreted from epithelia and can be found in nearly all fluids of the body. In adipocytes, AZGP1 triggers lipid degradation, that leads to a broad fat lost that can be linked to progressive type of cancers.
AZGP1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 283 amino acids (21-298 a.a) and having a molecular mass of 33.2kDa. AZGP1 is fused to a 5 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | AZGP1: Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. May bind polyunsaturated fatty acids. Belongs to the MHC class I family. |
| UniProt Protein Details: | Protein type:Cell adhesion; Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 7q22.1 Cellular Component: extracellular space; extracellular region; plasma membrane; nucleus; MHC class I protein complex Molecular Function:peptide antigen binding; protein transmembrane transporter activity; glycoprotein binding; antigen binding; ribonuclease activity Biological Process: retinal homeostasis; antigen processing and presentation; negative regulation of cell proliferation; antigen processing and presentation of peptide antigen via MHC class I; positive regulation of T cell mediated cytotoxicity; immune response; detection of chemical stimulus involved in sensory perception of bitter taste; cell adhesion |
| UniProt Code: | P25311 |
| NCBI GenInfo Identifier: | 292495049 |
| NCBI Gene ID: | 563 |
| NCBI Accession: | P25311.2 |
| UniProt Secondary Accession: | P25311,O60386, Q5XKQ4, Q8N4N0, D6W5T8, |
| UniProt Related Accession: | P25311 |
| Molecular Weight: | |
| NCBI Full Name: | Zinc-alpha-2-glycoprotein |
| NCBI Synonym Full Names: | alpha-2-glycoprotein 1, zinc-binding |
| NCBI Official Symbol: | AZGP1 |
| NCBI Official Synonym Symbols: | ZAG; ZA2G |
| NCBI Protein Information: | zinc-alpha-2-glycoprotein; zn-alpha-2-GP; Zn-alpha2-glycoprotein; zn-alpha-2-glycoprotein; Alpha-2-glycoprotein, zinc |
| UniProt Protein Name: | Zinc-alpha-2-glycoprotein |
| Protein Family: | Zinc-alpha-2-glycoprotein |
| UniProt Gene Name: | AZGP1 |
| UniProt Entry Name: | ZA2G_HUMAN |
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