Human ATG5 Recombinant Protein (RPES3181)

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SKU:
RPES3181
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human ATG5 Recombinant Protein

ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton.

Product Name:Human ATG5 Recombinant Protein (RPES3181)
Product Code:RPES3181
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Autophagy protein 5, APG5-like, Apoptosis-specific protein, APG5L, ASP, ATG5,
Accession:Q9H1Y0
Sequence:Met 1-Asp275
Fusion tag:
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Autophagy Related 5 Homolog is produced by our E.coli expression system and the target gene encoding Met1-Asp275 is expressed.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:32.4 kDa
AP Mol Mass:33 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM Tris,0.2M NaCl,1mM DTT,40%glycerol, pH 8.0 .
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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