Human ATG5 Recombinant Protein (RPES3181)
- SKU:
- RPES3181
- Product type:
- Recombinant Protein
- Host species:
- E.coli
- Reactivity:
- Human
Frequently bought together:
Description
system_update_alt데이터시트
Human ATG5 Recombinant Protein
ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton.
| Product Name: | Human ATG5 Recombinant Protein (RPES3181) |
| Product Code: | RPES3181 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Autophagy protein 5, APG5-like, Apoptosis-specific protein, APG5L, ASP, ATG5, |
| Accession: | Q9H1Y0 |
| Sequence: | Met 1-Asp275 |
| Fusion tag: | |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Autophagy Related 5 Homolog is produced by our E.coli expression system and the target gene encoding Met1-Asp275 is expressed. |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 32.4 kDa |
| AP Mol Mass: | 33 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM Tris,0.2M NaCl,1mM DTT,40%glycerol, pH 8.0 . |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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