Human ATG3 Recombinant Protein (RPES3124)

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SKU:
RPES3124
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human ATG3 Recombinant Protein

Ubiquitin-like-conjugating enzyme ATG3 (ATG3), also known as Apg3L and Apg3p, functions as a regulatory component of autophagosome biogenesis necessary for autophagy. ATG3 exhibits 98% aa sequence identity with both its mouse and rat orthologs. It is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. As an E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential for autophagy. ATG3 also can catalyze the conjugation of ATG12 to itself which palys a role in mitochondrial homeostasis but not in autophagy.

Product Name:Human ATG3 Recombinant Protein (RPES3124)
Product Code:RPES3124
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Ubiquitin-like-conjugating enzyme ATG3, Autophagy-related protein 3, APG3-like, hApg3, Protein PC3-96, ATG3, APG3, APG3L
Accession:Q9NT62
Sequence:Met 1-Met314
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Ubiquitin-like-conjugating Enzyme ATG3/ATG3 is produced by our E.coli expression system and the target gene encoding Met1-Met314 is expressed.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:36 kDa
AP Mol Mass:38 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM TrisHCl,150mM NaCl,10% Glycerol,pH 8.0.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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