Human ART4 Recombinant Protein (RPPB1415)
- SKU:
- RPPB1415
- Product type:
- Recombinant Protein
- Size:
- 5ug
- Species:
- Human
- Target:
- ART4
- Synonyms:
- ARTC4
- DOK1
- CD297 Antigen
- Dombrock Blood Group
- Source:
- Sf9 Insect cells
- Uniprot:
- Q93070
Frequently bought together:
Description
| Product Name: | Human ART4 Recombinant Protein |
| Product Code: | RPPB1415 |
| Size: | 5µg |
| Species: | Human |
| Target: | ART4 |
| Synonyms: | ARTC4, DOK1, CD297 Antigen, Dombrock Blood Group, ADP-Ribosyltransferase 4, Ecto-ADP-Ribosyltransferase 4. |
| Source: | Sf9 Insect cells |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | ART4 protein solution (0.25mg/ml) contains Buffered Saline (pH 7.4) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | ADPSEVAIKI DFDFAPGSFD DQYQGCSKQV MEKLTQGDYF TKDIEAQKNY FRMWQKAHLA WLNQGKVLPQ NMTTTHAVAI LFYTLNSNVH SDFTRAMASV ARTPQQYERS FHFKYLHYYL TSAIQLLRKD SIMENGTLCY EVHYRTKDVH FNAYTGATIR FGQFLSTSLL KEEAQEFGNQ TLFTIFTCLG APVQYFSLKK EVLIPPYELF KVINMSYHPR GDWLQLRSTG NLSTYNCQLL KAHHHHHH |
Ecto-ADP-Ribosyltransferase 4 or ART4 is typed as a glycosylphosphatidylinositol (GPI)-linked membrane protein which carries Dombrock blood group antigens. The development of this protein takes place at the highest levels in the fetal liver. the process of the ART4 development is regulated while the erythroid differentiation process occurs. ART4 is a is part of the Ribosyltransferase family.
ART4 produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 248 amino acids (47-285 a.a.) and having a molecular mass of 28.8kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa). ART4 is expressed with a 9 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
| NCBI Summary: | This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. Antigens of the Dombrock blood group system are located on the gene product, which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane. Allelic variants, some of which lead to adverse transfusion reactions, are known. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q93070 |
| NCBI GenInfo Identifier: | 22261809 |
| NCBI Gene ID: | 420 |
| NCBI Accession: | Q93070.2 |
| UniProt Related Accession: | Q93070 |
| Molecular Weight: | 36kDa |
| NCBI Full Name: | Ecto-ADP-ribosyltransferase 4 |
| NCBI Synonym Full Names: | ADP-ribosyltransferase 4 (Dombrock blood group) |
| NCBI Official Symbol: | ART4 |
| NCBI Official Synonym Symbols: | DO; DOK1; ARTC4; CD297; DO/ART4 |
| NCBI Protein Information: | ecto-ADP-ribosyltransferase 4 |
| UniProt Protein Name: | Ecto-ADP-ribosyltransferase 4 |
| UniProt Synonym Protein Names: | ADP-ribosyltransferase C2 and C3 toxin-like 4; ARTC4; Dombrock blood group carrier molecule; Mono(ADP-ribosyl)transferase 4; NAD(P)(+)--arginine ADP-ribosyltransferase 4; CD_antigen: CD297 |
| Protein Family: | Ecto-ADP-ribosyltransferase |
| UniProt Gene Name: | ART4 |
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