Human Angiogenin/ANG Recombinant Protein (RPES2481)
- SKU:
- RPES2481
- Product type:
- Recombinant Protein
- Host species:
- E.coli
- Reactivity:
- Human
Frequently bought together:
Description
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Human Angiogenin/ANG Recombinant Protein
Angiogenin belongs to the pancreatic ribonuclease family. Angiogenin is primarily expressed in the liver. It may act as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Angiogenin is a potent stimulator of new blood vessel formation. And Angiogenin is endocytosed and translocated to the nucleus by binding to actin on the surface of endothelial cells. Angiogenic activity is regulated by interaction with RNH1 in vivo. In addition, Angiogenin is associated with susceptibility to amyotrophic lateral sclerosis, which is a degenerative disorder of motor neurons in the cortex, brain stem and spinal cord.
| Product Name: | Human Angiogenin/ANG Recombinant Protein (RPES2481) |
| Product Code: | RPES2481 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Angiogenin, Ribonuclease 5, RNase 5, ANG, RNASE5 |
| Accession: | P03950 |
| Sequence: | Gln25-Pro147 |
| Fusion tag: | |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Angiogenin is produced by our E.coli expression system and the target gene encoding Gln25-Pro147 is expressed. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 14.3 kDa |
| AP Mol Mass: | 14 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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