Human Amphiregulin/AREG Recombinant Protein (RPES2440)
- SKU:
- RPES2440
- Product type:
- Recombinant Protein
- Host species:
- E.coli
- Reactivity:
- Human
Frequently bought together:
Description
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Human Amphiregulin/AREG Recombinant Protein
Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is expressed in a variety of tissues including ovary, placenta, lung, kidney, stomach, colon, and breast. It is related to Epidermal Growth Factor (EGF) and Transforming Growth Factor Alpha (TGF-alpha). As an EGF-related growth factor, AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. AREG may also play a protective role in Bleomycin-Induced Pneumopathy.
Product Name: | Human Amphiregulin/AREG Recombinant Protein (RPES2440) |
Product Code: | RPES2440 |
Size: | 10µg |
Species: | Human |
Expressed Host: | E.coli |
Synonyms: | Amphiregulin, AR, Colorectum Cell-Derived Growth Factor, CRDGF, AREG, SDGF, AREGB |
Accession: | P15514 |
Sequence: | Ser101-Lys198 |
Fusion tag: | |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | Recombinant Human Amphiregulin is produced by our E.coli expression system and the target gene encoding Ser101-Lys198 is expressed. |
Purity: | > 95 % as determined by reducing SDS-PAGE. |
Mol Mass: | 11.4 kDa |
AP Mol Mass: | 16 kDa |
Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |