Human Amphiregulin/AREG Recombinant Protein (RPES2440)

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SKU:
RPES2440
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human Amphiregulin/AREG Recombinant Protein

Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is expressed in a variety of tissues including ovary, placenta, lung, kidney, stomach, colon, and breast. It is related to Epidermal Growth Factor (EGF) and Transforming Growth Factor Alpha (TGF-alpha). As an EGF-related growth factor, AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. AREG may also play a protective role in Bleomycin-Induced Pneumopathy.

Product Name:Human Amphiregulin/AREG Recombinant Protein (RPES2440)
Product Code:RPES2440
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Amphiregulin, AR, Colorectum Cell-Derived Growth Factor, CRDGF, AREG, SDGF, AREGB
Accession:P15514
Sequence:Ser101-Lys198
Fusion tag:
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Amphiregulin is produced by our E.coli expression system and the target gene encoding Ser101-Lys198 is expressed.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:11.4 kDa
AP Mol Mass:16 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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