Human AMIGO2 Recombinant Protein (RPPB2731)

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SKU:
RPPB2731
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
AMIGO2
Synonyms:
AdhesionMolecule with Ig-Like Domain 2
Synonyms:
Differentially Expressed in Gastric
Synonyms:
Adenocarcinomas
Synonyms:
AMIGO-2
Source:
Sf9 Insect cells
Uniprot:
Q86SJ2
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Description

Product Name:Human AMIGO2 Recombinant Protein
Product Code:RPPB2731
Size:10µg
Species:Human
Target:AMIGO2
Synonyms:AdhesionMolecule with Ig-Like Domain 2, Differentially Expressed in Gastric, Adenocarcinomas,AMIGO-2, ALI1, DEGA, Differentially Expressed in Gastric, Adenocarcinoma, Amphoterin-InducedGene and Open Reading Frame 2, Transmembrane Protein AMIGO2, Amphoterin InducedGene, Alivin 1, Alivin-1.
Source:Sf9 Insect cells
Physical Appearance:Sterilefiltered colorless solution.
Formulation:AMIGO2protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10%glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greaterthan 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:VCPTACICAT DIVSCTNKNL SKVPGNLFRL IKRLDLSYNR IGLLDSEWIP VSFAKLNTLILRHNNITSIS TGSFSTTPNL KCLDLSSNKL KTVKNAVFQE LKVLEVLLLY NNHISYLDPS AFGGLSQLQK LYLSGNFLTQ FPMDLYVGRF KLAELMFLDV SYNRIPSMPM HHINLVPGKQ LRGIYLHGNP FVCDCSLYSL LVFWYRRHFS SVMDFKNDYT CRLWSDSRHS RQVLLLQDSF MNCSDSIING SFRALGFIHE AQVGERLMVH CDSKTGNANT DFIWVGPDNR LLEPDKEMEN FYVFHNGSLV IESPRFEDAG VYSCIAMNKQ RLLNETVDVT INVSNFTVSR SHAHEAFNTL EHHHHHH

Adhesion Molecule with Ig-Like Domain 2, also known as AMIGO2 is a memberof the leucine-rich repeat family. AMIGO2 arbitrates homophilic in addition toheterophilic cell-cell interaction with AMIGO1 or AMIGO3. Furthermore, AMIGO2 contributes to signal transduction via its intracellular domain and isalso essential for tumorigenesis of a subset of gastric adenocarcinomas.

AMIGO2 produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 367 amino acids (40-398a.a.) and having a molecular mass of 41.9kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa).AMIGO2 is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

UniProt Protein Function:Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q86SJ2
NCBI GenInfo Identifier:219521831
NCBI Gene ID:347902
NCBI Accession:NP_001137140.1
UniProt Secondary Accession:Q86SJ2,Q4VBP6, Q7Z4A0, Q96CN8
UniProt Related Accession:Q86SJ2
Molecular Weight:57
NCBI Full Name:amphoterin-induced protein 2
NCBI Synonym Full Names:adhesion molecule with Ig like domain 2
NCBI Official Symbol:AMIGO2  
NCBI Official Synonym Symbols:ALI1; DEGA; AMIGO-2  
NCBI Protein Information:amphoterin-induced protein 2
UniProt Protein Name:Amphoterin-induced protein 2
UniProt Synonym Protein Names:AMIGO-2; Alivin-1; Differentially expressed in gastric adenocarcinomas; DEGA
Protein Family:
UniProt Gene Name:AMIGO2  
UniProt Entry Name:
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