Human ACBD6 Recombinant Protein (RPPB2697)
- SKU:
- RPPB2697
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- ACBD6
- Synonyms:
- Acyl-CoA Binding Domain Containing 6
- Acyl-Coenzyme ABinding Domain Containing 6
- Acyl-CoA-Binding Domain-Containing Protein 6
- ACBD6
- Source:
- Escherichia Coli
- Uniprot:
- Q9BR61
Description
| Product Name: | Human ACBD6 Recombinant Protein |
| Product Code: | RPPB2697 |
| Size: | 20µg |
| Species: | Human |
| Target: | ACBD6 |
| Synonyms: | Acyl-CoA Binding Domain Containing 6, Acyl-Coenzyme ABinding Domain Containing 6, Acyl-CoA-Binding Domain-Containing Protein 6, ACBD6. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | ACBD6 protein solution (0.5mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMASSFLP AGAITGDSGG ELSSGDDSGE VEFPHSPEIE ETSCLAELFE KAAAHLQGLI QVASREQLLY LYARYKQVKV GNCNTPKPSF FDFEGKQKWE AWKALGDSSP SQAMQEYIAV VKKLDPGWNP QIPEKKGKEA NTGFGGPVIS SLYHEETIRE EDKNIFDYCR ENNIDHITKA IKSKNVDVNV KDEEGRALLH WACDRGHKEL VTVLLQHRAD INCQDNEGQT ALHYASACEF LDIVELLLQS GADPTLRDQD GCLPEEVTGC KTVSLVLQRH TTGKA |
Acyl-CoAbinding domain containing 6, also known as ACBD6 contains 1 ACB(acyl-CoA-binding) domain and 2 ANK repeats. ACBD6 binds long-chainacyl-coenzyme A molecules with a strong preference for unsaturated C18:1 CoA,lower affinity for unsaturated C20:4-CoA, and extremely weak affinity forsaturated C16:0-CoA. Moreover ACBD6 doesnot bind fatty acids. ACBD6 has been detected in placenta, umbilical cordblood, CD34-positive hematopoietic progenitor cells and bone marrow.Endotheliitis has been associated with ACBD6.
ACBD6 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 305 amino acids (1-282aa) and having a molecular mass of 33.5kDa.ACBD6 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | ACBD6: Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0- CoA. Does not bind fatty acids. |
| UniProt Protein Details: | Protein type:Lipid-binding Chromosomal Location of Human Ortholog: 1q25.3 Cellular Component: cytoplasm Molecular Function:acyl-CoA binding; lipid binding |
| UniProt Code: | Q9BR61 |
| NCBI GenInfo Identifier: | 74762703 |
| NCBI Gene ID: | 84320 |
| NCBI Accession: | Q9BR61.1 |
| UniProt Secondary Accession: | Q9BR61,Q9D061, Q5RJK8, |
| UniProt Related Accession: | Q9BR61 |
| Molecular Weight: | 31,151 Da |
| NCBI Full Name: | Acyl-CoA-binding domain-containing protein 6 |
| NCBI Synonym Full Names: | acyl-CoA binding domain containing 6 |
| NCBI Official Symbol: | ACBD6 |
| NCBI Protein Information: | acyl-CoA-binding domain-containing protein 6 |
| UniProt Protein Name: | Acyl-CoA-binding domain-containing protein 6 |
| Protein Family: | Acyl-CoA-binding domain-containing protein |
| UniProt Gene Name: | ACBD6 |
| UniProt Entry Name: | ACBD6_HUMAN |
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